Alpha-adrenergic agonists are a class of medications that work via a dual mechanism to lower intraocular pressure, and some believe they also have a direct protective effect on the optic nerve.

Mechanism of Action

This class reduces the production of fluid inside the eye and additionally increases the drainage of fluid through the uveoscleral (secondary) pathway. The drops are typically administered two to three times a day.

Potential Side Effects

The most common side effects include local eye allergy (which can appear even months after starting treatment), fatigue, and dry mouth. If the eye becomes red, itchy, and swollen, you must stop the treatment and consult a doctor immediately.